The drug works by blocking a protein called USAG-1, which normally prevents tooth growth. When this protein is suppressed, the body activates its hidden ability to grow replacement teeth a trait seen in sharks and reptiles. In early trials, mice and ferrets successfully grew completely new teeth, and human clinical trials are now underway in Japan.
If successful, this treatment could eliminate the need for dentures, dental implants, and false teeth forever. People who lost teeth due to age, disease, or accidents may soon be able to grow new ones naturally. The drug is expected to be ready for public use by 2030, making it one of the most anticipated medical innovations of the decade.
This breakthrough doesn’t just change dentistry — it changes human biology.
The possibility of natural tooth regeneration could dramatically improve quality of life for millions worldwide.